Sleep Disorder Connect
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SLeep Education for Everyone Program (SLEEP) Results in Sustained Improvements in Sleep Outcomes at Six Months - PubMed

SLeep Education for Everyone Program (SLEEP) Results in Sustained Improvements in Sleep Outcomes at Six Months - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/36377788/

doi: 10.1080/15402002.2022.2146693. Online ahead of print. 1 Office of Research and Education, Spectrum Health West Michigan, Grand Rapids, Michigan. 2 Michigan State University Extension. Michigan State University, East Lansing, Michigan....


Conclusions: These results suggest that a community-delivered sleep education intervention can produce sustained benefits for participants and should be considered as a tool to address uncomplicated sleep issues.


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Understanding and approaching excessive daytime sleepiness

Understanding and approaching excessive daytime sleepiness

Source : https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01018-2/fulltext

Excessive daytime sleepiness (EDS) is a public health issue. However, it remains largely undervalued, scarcely diagnosed, and poorly supported. Variations in the definition of EDS and limitations in clinical assessment...


Conclusions: Because of the heterogeneous causes of EDS and the complexity of its pathophysiology, management will largely depend on the cause, with the final aim of making treatment specific to the individual using precision medicine and personalised medicine.


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The relationship between Alzheimer's-related brain atrophy patterns and sleep macro-architecture - PubMed

The relationship between Alzheimer's-related brain atrophy patterns and sleep macro-architecture - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/36381559/

1 Department of Psychiatry and Psychotherapy University Medicine Greifswald Greifswald Mecklenburg-Vorpommern Germany. 2 German Centre for Neurodegenerative Diseases (DZNE) Site Rostock/Greifswald Greifswald Mecklenburg-Vorpommern Germany. 3 Department of Internal Medicine B-Cardiology...


Discussion: There is a cross-sectional relationship between AD-related neurodegenerative patterns and the proportion of sleep spent in slow-wave sleep."


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Efficacy and Safety of Lower-Sodium Oxybate in an Open-Label Titration | NSS

Efficacy and Safety of Lower-Sodium Oxybate in an Open-Label Titration | NSS

Source : https://www.dovepress.com/efficacy-and-safety-of-lower-sodium-oxybate-in-an-open-label-titration-peer-reviewed-fulltext-article-NSS

Idiopathic hypersomnia is a sleep disorder that causes daytime sleepiness. Many patients also have difficulty awakening, long sleep time at night, long and unrefreshing naps, and problems thinking clearly. Lower-sodium...


Conclusions: During open-label treatment with LXB, participants showed clinically meaningful improvements in idiopathic hypersomnia symptoms and in quality of life and functional measures. TEAE incidence declined over LXB titration and optimization.

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    Key Points • Source: Nature and Science of Sleep • Relevance: “These results show that lower-sodium oxybate improved symptoms of idiopathic hypersomnia and improved participants’ quality of life, day-to-day functioning, and ability to work. Show More
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Daridorexant, a recently approved Dual Orexin Receptor Antagonists (DORA) in the treatment of insomnia

Daridorexant, a recently approved Dual Orexin Receptor Antagonists (DORA) in the treatment of insomnia

Source : https://www.eurekaselect.com/article/127449

Insomnia is one of the major challenges in medical science now a days as it leads to great socio-economic burden by impairing the daytime function as well as development of...


Conclusions: Conclusions/Relevance: Beyond the effectiveness in insomnia, it has been successfully used in patients suffering from Obstructive sleep apnoea, Chronic Obstructive Airway Disease (COAD), Alzheimer’s Disease (AD), hypertension and cardiovascular disorders. Larger studies need to address the safety issues as well as obtaining robust...