The curious case of the Z's - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36740920/
Excessive daytime sleepiness (EDS) is a common presenting symptom that may present a diagnostic challenge for the sleep medicine clinician. We present a case of an adolescent female with EDS...
Conclusions: This case highlights the importance of thorough clinical evaluation, and careful interpretation of objective tests, when evaluating for causes of EDS.
The abuse potential of lemborexant, a dual orexin receptor antagonist, according to the 8 factors of the Controlled Substances Act - Psychopharmacology
Source : https://link.springer.com/article/10.1007/s00213-023-06320-y
Rationale Lemborexant (LEM) is a dual orexin receptor antagonist (DORA) approved in multiple countries including the USA, Japan, Canada, Australia, and several Asian countries for the treatment of insomnia in...
Conclusions: LEM, similar to most other prescription insomnia medications, was placed into Schedule IV. However, LEM and other drugs in the DORA class may have a lower potential for abuse as suggested by real-world postmarketing data from federal surveys and internet surveillance, and thus may have lower risks to public health than Schedule IV...
Discrepancies Between Caregiver Reported Early Childhood Sleep Problems and Clinician Documentation and Referral
Source : https://www.academicpedsjnl.net/article/S1876-2859(23)00016-5/fulltext
The American Academy of Pediatrics (AAP) recommends routine sleep problem screenings during child well-visits. However, studies suggest a discrepancy between caregiver- and clinician-reported child sleep problems. The present study examines...
Conclusions: There is a vast discrepancy between caregiver-reported child sleep problems and clinician-documented sleep problems and management, with a higher proportion of caregiver reports. To benefit overall child health and well-being, future research and quality improvement initiatives should focus on enhancing screening tools and...
Association of sleep behaviors with white matter hyperintensities and microstructural injury: a cross-sectional and longitudinal analysis of 26,354 participants - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36728016/
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Conclusions: Unhealthy sleep behaviors were associated with increased WMH burden and worse white matter microstructure in specific tracts across middle and older age. These findings provide the potential to improve white matter integrity by reversing unhealthy sleep behaviors.
Sleep clusters and modifiable risk behaviors for noncommunicable diseases in young adults: Data from a birth cohort in Brazil
Source : https://www.sciencedirect.com/science/article/abs/pii/S2352721823000037?via=ihub
Available online 24 January 2023 Author links open overlay panel Adriana Kramer Fiala Machado PhD a , , , , Show more To determine sleep clusters among young adults and...
Conclusions: Poor sleep health is associated with higher prevalence of modifiable risk behaviors for NCDs. Prevention strategies for NCDs should also focus on sleep health.