Burden of corticosteroid therapy in patients with immunoglobulin A nephropathy (IgAN): a systematic literature review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40389892/
Current guidelines recommend short-term corticosteroid treatment for patients at high risk of progression but long-term use appears to be widespread. Corticosteroids may lead to adverse outcomes and should therefore be...
This review highlights the global burden of corticosteroid therapy in IgAN, noting long-term use is common and linked to increased adverse events, including metabolic effects and sleep disorders.
Sleep-Disordered Breathing and Hypertension-A Systematic Review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40364148/
Background/Objectives: Sleep-disordered breathing (SDB), historically referred to as "sleep apnea syndrome", particularly obstructive sleep apnea (OSA), is an independent risk factor for hypertension (HTN), stroke, heart failure, arrhythmias, and other...
This systematic review examines the link between obstructive sleep apnea and hypertension, highlighting their joint impact on cardiovascular health and advocating for multimodal treatment approaches to improve patient outcomes.
Ventilation in the obese: physiological insights and management - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40368425/
Obesity can have profound adverse effects on the respiratory system, including an impact on pulmonary function, respiratory mechanics, respiratory muscle strength and endurance, gas exchange, control of breathing, and exercise...
Obesity alters respiratory mechanics and gas exchange, contributing to conditions like OSA and OHS. This review explores physiological changes and ventilatory management strategies in obese patients with sleep-related breathing disorders.
Characterizing Patient-Reported Fatigue Using Electronic Diaries in Neurodegenerative and Immune-Mediated Inflammatory Diseases: Observational Study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40324214/
This study demonstrates the feasibility, acceptability, and validity of using high-frequency eDiaries to assess fatigue in chronic conditions. By effectively detecting intra- and interday fatigue variations, eDiaries complement traditional PROs...
This observational study used electronic diaries to track real-time fatigue in patients with neurodegenerative and immune-mediated inflammatory diseases, revealing daily fluctuations and demonstrating moderate correlation with traditional fatigue assessments.
This study outlines a randomized trial investigating augmented reality (AR) as a tool to improve CPAP therapy adherence in obstructive sleep apnea patients through interactive education and real-time guidance.