Lower-Sodium Oxybate Dose Titration and Transition From Sodium Oxybate in a Placebo-Controlled, Double-Blind, Randomized Withdrawal Study in Adult Participants With Narcolepsy With Cataplexy (2163)
Source : https://n.neurology.org/content/96/15_Supplement/2163
Objective: Evaluate dose adjustment of calcium, magnesium, potassium, and sodium oxybates (lower-sodium oxybate, LXB; Xywav™; previously designated as JZP-258) during titration in a double-blind, placebo-controlled, randomized withdrawal study. Background: Sodium...
CAT-CAD: A Computer-Aided Diagnosis Tool for Cataplexy
Source : https://www.mdpi.com/2073-431X/10/4/51
Narcolepsy with cataplexy is a severe lifelong disorder characterized, among others, by sudden loss of bilateral face muscle tone triggered by emotions (cataplexy). A recent approach for the diagnosis of...
Neurophysiology of Basic Molecules Affecting Sleep and Wakefulness Mechanisms, Fundamentals of Sleep Pharmacology
Source : https://www.intechopen.com/online-first/78603
As part of the biological rhythm, the human brain has a healthy functioning with the ability to differentiate between day and night hours in any given day (sleep rhythm, life...
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Dr Hamid4yrThe more we learn about the neurophysiology of sleep and the effects of related molecules, the better we understand the pathological processes in wakefulness !
Narcolepsy: the impact of aging, hypocretin deficiency, and years of formal education in olfactory function and abdominal obesity.
Source : https://europepmc.org/article/med/34495122
Background Narcolepsy is a disease resulting from the loss of hypocretin-producing cells or other dysfunctions of the hypocretinergic system. In addition to sleep disorders, affected patients may experience increased weight...
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Dr Hamid4yraging and hypocretin deficiency are associated with abdominal obesity, while years of study is the variable that mostly influences olfaction function.
Association between asthma and narcolepsy | NSS
Narcolepsy is a neurological disorder that affects the brain's ability to control sleep and wakefulness. There are two main types of narcolepsy: type 1 and type 2. All types of...
Conclusion: This study demonstrated a significantly higher level of previous asthma diagnosis in patients with narcolepsy. The use of inhaled corticosteroids was associated with a lower risk of narcolepsy comorbidity in asthma patients, compared to those without treatment.
Conclusion: This study demonstrated a significantly higher level...