Images: Facial cataplexy with demonstration of persistent eye movement

Source : https://jcsm.aasm.org/doi/10.5664/jcsm.8148

The prevailing pathophysiological concept of narcolepsy is one of sleep-wake instability, whereby elements of sleep physiology can impose themselves on wakefulness and vice versa. Cataplexy is felt to be one...

Risk factors for sleep disorders in patients undergoing peritoneal dialysis - Sleep and Biological Rhythms

Source : https://link.springer.com/article/10.1007/s41105-021-00311-2

Sleep disorders in patients with end-stage renal disease are common but have rarely been reported in previous studies. Therefore, we examined the prevalence of sleep disorders and the risk factors...

Neurobiology of cataplexy

Source : https://doi.org/10.1016/j.smrv.2021.101546

Does sodium oxybate inhibit brain dopamine release in humans? An exploratory neuroimaging study

Source : https://onlinelibrary.wiley.com/doi/abs/10.1002/hup.2791

To establish in an exploratory neuroimaging study whether γ-hydroxybutyrate (sodium oxybate [SO]), a sedative, anti-narcoleptic drug with abuse potential, transiently inhibits striatal dopamine release in the human.

Association of Central Hypersomnia and Fatigue in Patients With Multiple Sclerosis

Source : https://n.neurology.org/content/97/1/e23.abstract

Objective To evaluate sleepiness and central hypersomnia in multiple sclerosis (MS)-associated fatigue, we performed long-term polysomnography in patients with MS and healthy controls. Methods Patients with MS and healthy controls...