Clinicopathologic variables ranked as highly important to corticolimbic vulnerability were age at symptomatic onset, disease duration, Braak stage, and nonamnestic clinical syndrome.
Disruptions of Gut Microbiota Are Associated With Cognitive Deficit of Preclinical Alzheimer's Disease: a Cross-Sectional Study
Source : https://www.eurekaselect.com/article/139376
Background: Alzheimer's Disease (AD) is the most prevalent type of dementia. The early change of gut microbiota is a potential biomarker for preclinical AD patients. Objective: The study aimed to...
Bifidobacterium adolescentis was associated with better performance in multiple cognitive scores and several serum indicators, and Roseburia inulinivorans showed negative correlations with the scores of the Functional Activities Questionnaire.
Assessing the Impact of an Online Dementia Awareness Initiative Co-Created With and for English, Arabic and Vietnamese Speaking Communities: a Case Study
Source : https://pubmed.ncbi.nlm.nih.gov/38618991/
English, Arabic and Vietnamese speaking members of the Canterbury Bankstown Dementia Alliance participated in the co-creation and evaluation of this initiative.
The initiative was hindered by competing priorities and limited accessibility to target audiences, while it was helped by the support of an established organization and feedback mechanisms.
What Is Alzheimer's Disease? An Analysis of Nosological Perspectives From the 20th and 21st Centuries
Source : https://pubmed.ncbi.nlm.nih.gov/38618742/
This historical perspective illustrates the unresolved questions surrounding AD pathogenesis, role of lesions, and the clinical phenotype, especially for sporadic cases. The intense nosological debates throughout the history of AD...
This historical perspective illustrates the unresolved questions surrounding AD pathogenesis, role of lesions, and the clinical phenotype, especially for sporadic cases.
Land/Water Aerobic Activities: Two Sides of the Same Coin. A Comparative Analysis on the Effects in Cognition of Alzheimer's Disease
Source : https://pubmed.ncbi.nlm.nih.gov/38552114/
Evidence in the literature indicates that aerobic physical activity may have a protective role in aging pathologies. However, it has not been clarified whether different types of aerobic exercise produce...
Aerobic exercise promoted brain functioning through the secretion of molecular factors, which stimulated neuroplasticity, reduced neuroinflammation, and inhibited neurodegenerative processes.