Disease Spotlight
Agitation in Alzheimer's Dementia
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Reduction and prevention of agitation in persons with neurocognitive disorders: an international psychogeriatric association consensus algorithm - PubMed

Reduction and prevention of agitation in persons with neurocognitive disorders: an international psychogeriatric association consensus algorithm - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/36876335/

The IPA definition of agitation is operationalized into an agitation management algorithm that emphasizes the integration of psychosocial and pharmacologic interventions, reiterative assessment of response to treatment, adjustment of therapeutic...

The IPA Agitation Workgroup developed an algorithm for agitation reduction, emphasizing investigation, planning, shared decision-making, psychosocial and pharmacologic interventions, and repeated assessment to adjust treatment for optimal outcomes.

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Did you know? In Rhode Island, integrated behavioral health interventions led to a significant reduction in health care utilization. Emergency department visits dropped by 6.4 per 1,000 people per month, and office visits decreased by 29.8 per 1,000 people per month, reflecting a 7% and 6% reduction, respectively. This highlights the positive impact of behavioral health integration on overall health care demand.

How can expanding integrated behavioral health programs further reduce health care utilization and improve patient outcomes across communities?

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How can expanding integrated behavioral health programs further reduce health care utilization and improve patient outcomes across communities?

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Alzheimer's Disease: A Suitable Case for Treatment with Precision Medicine? - PubMed

Alzheimer's Disease: A Suitable Case for Treatment with Precision Medicine? - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38471490/

Alzheimer's disease (AD) is the most common cause of neurodegenerative impairment in elderly people. Clinical characteristics include short-term memory loss, confusion, hallucination, agitation, and behavioural disturbance. Owing to evolving research...

Alzheimer's disease (AD) research focuses on early detection, preclinical phase treatment, and precision medicine. Advances include antisense molecules, antibodies, antioxidants, small molecules, and gene editing to halt or reverse AD progression.

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Clinical Pipelines for Alzheimer's Disease Psychosis and Agitation - PubMed

Clinical Pipelines for Alzheimer's Disease Psychosis and Agitation - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38945937/

Agitation and psychosis are key behavioral and psychological symptoms of Alzheimer's disease (AD). For family and caregivers of patients, such symptoms are critical factors of distress and increased burden, but...

Brexpiprazole, approved by the FDA in 2023, is the first drug for treating agitation in Alzheimer's disease. Ongoing research explores additional therapies for managing agitation and psychosis in AD patients.

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This case series investigates the proportion of US counties and the overall population served by certified community behavioral health clinics (CCBHCs) from October 2016 to June 2024. CCBHCs play a vital role in enhancing behavioral health care quality and availability. The study examines the distribution and accessibility of these clinics, focusing on the impact of federal investments, including over $1.7 billion in expansion grants. Understanding the geographical spread of CCBHCs will shed light on whether their growth benefits specific areas or promotes equitable access nationwide, crucial for future policy decisions and funding strategies.

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