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High nocturnal sleep fragmentation is associated with low T lymphocyte P2Y11 protein levels in narcolepsy type 1

High nocturnal sleep fragmentation is associated with low T lymphocyte P2Y11 protein levels in narcolepsy type 1

Source :

https://academic.oup.com/sleep/advance-article/doi/10.1093/sleep/zsab062/6168886?login=true

This is the first study to explore associations between clinical and sleep phenotype parameters, the P2RY11 polymorphism rs2305795 genotype, and P2Y 11 protein levels in a large mainly H1N1-(Pandemrix)-vaccinated cohort of NT1 patients and their first-degree relatives. We confirm that the P2RY11 A risk allele predisposes towards NT1 in our cohort.