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Solriamfetol treatment of excessive daytime sleepiness in participants with narcolepsy or obstructive sleep apnea with a history of depression

Solriamfetol treatment of excessive daytime sleepiness in participants with narcolepsy or obstructive sleep apnea with a history of depression

Source :

https://www.sciencedirect.com/science/article/abs/pii/S002239562200471X?via=ihub

Solriamfetol treatment outcomes were analyzed according to depression history. * Depression history was prevalent in people with narcolepsy/obstructive sleep apnea. * Solriamfetol improved excessive daytime sleepiness regardless of depression history. * Concomitant antidepressant use did not affect response to solriamfetol. * Safety/tolerability was similar regardless of depression history/antidepressant use.


Conclusions: Civilian sleep specialists were twice as likely to diagnose central disorders of hypersomnolence compared to military specialists. Raising awareness about this discrepancy is critical given the occupational and patient care-related implications of misdiagnoses.