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Quality of life changes and their predictors in young adult narcolepsy patients after treatment: A real-world cohort study

Quality of life changes and their predictors in young adult narcolepsy patients after treatment: A real-world cohort study

Source :

https://www.frontiersin.org/articles/10.3389/fpsyt.2022.956037/full

BackgroundWe conducted a five-year prospective follow-up study to track the real-world quality of life of patients with narcolepsy after medication and analyzed predictors.MethodsThe study ultimately included 157 participants who completed 5-year follow-up, 111 had type 1 narcolepsy (NT1) and 46 had type 2 narcolepsy (NT2). Polysomnography, multiple sleep latency test, actigraphy and HLA-typing were conducted.


Conclusion: Symptom control greatly associates with the quality of life in narcoleptic patients, and medication can play the most important role. Management targeting narcoleptic symptoms, attention impairment, and drug adherence should be provided.