Brandon Seay
from
Pulmonologist Connect
1 week 3 days
Narcolepsy would be on top of my differential. Start with a PSG and MSLT
Effect of Sleep Disorders on Blood Pressure and Hypertension in Children
Purpose of Review In this review, we aim to discuss the pathophysiologic basis of hypertension in sleep disorders and the current evidence in the medical literature linking sleep disorders and ..... see more
Source : https://link.springer.com/article/10.1007/s11906-020-01100-x
Living with narcolepsy during adolescence: A qualitative study
RATIONALE: Narcolepsy is a chronic sleep disorder, with typical onset in childhood or adolescence. Features of narcolepsy include excessive daytime sleepiness (EDS), cataplexy, sleep paralysis, hallucinations and disturbed nocturnal sleep. ..... see more
Enhanced influenza A H1N1 T cell epitope recognition and cross-reactivity to protein-O-mannosyltransferase 1 in Pandemrix-associated narcolepsy type 1
Narcolepsy type 1 (NT1) is a severe sleep disorder with strong association to the HLA type DQB1*0602 and increased incidence among children vaccinated with the Influenza A vaccine Pandemrix. Here ..... see more
Dissociative Symptoms are Highly Prevalent in Adults with Narcolepsy Type 1 - PubMed
Introduction : The core symptoms of narcolepsy such as excessive daytime sleepiness and cataplexy are well known. However, there is mounting evidence for a much broader symptom spectrum, including psychiatric ..... see more
High nocturnal sleep fragmentation is associated with low T lymphocyte P2Y11 protein levels in narcolepsy type 1 - PubMed
We confirmed that the P2RY11 polymorphism rs2305795 is associated with NT1 also in a mainly H1N1-(Pandemrix™)-vaccinated cohort. We demonstrated that homozygosity for the A risk allele is associated with lower ..... see more
Sleep Paralysis - A Comprehensive Study
A transient state of inability to move and to speak at sleep onset (hypnagogic form) or on awakening (hypnopompic form).Patients are subjectively awake and engaged in a mental struggle to ..... see more
Source : https://periodicparalysis.org/sleep-paralysis-a-comprehensive-study/
The Impact of Symptom Severity on Health-Related Quality of Life in Patients with Narcolepsy
Background: Narcolepsy has deleterious implications on daily life. However, few studies have fully assessed the severity of pentad symptoms of Chinese adults with narcolepsy type 1 (NT1), as well as ..... see more
Excessive Daytime Sleepiness in Japanese-American Male
History of Present Illness
Patient is a 22-year-old Asian-American male born in the U.S. Patient presents with symptoms .....
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MARK OVESON from Doctor Unite 2 weeks 6 days
Age and symptoms could indicate narcolepsy , I would ask about cataplexy, hypnagogic hallucinations and sleep paralysis .i Would get a sleep study and consider provigil.
Effects of vertical gastrectomy on sleep quality, eating behavior, and metabolic parameters in obese adults: a case study
ABSTRACT Obesity is a serious, chronic, and progressive disease associated with physiological dysfunctions that interact with circadian clock activity. Vertical gastrectomy (VG) is currently the most frequently performed bariatric procedure ..... see more
Source : https://www.tandfonline.com/doi/abs/10.1080/09291016.2021.1906504?journalCode=nbrr20&
Narcolepsy and psychosis: a systematic review - PubMed
Epidemiological studies tentatively suggest a possible association between narcolepsy and schizophrenia only for very early-onset cases, which could be related to the partially overlapping neurodevelopmental changes observed in these disorders. ..... see more
What Is Wrong with My Child? Narcolepsy and Its Emotional Burden on Parents
Anna Wani Rachel Rosen S. Kamal Naqvi Narcolepsy is a lifelong disorder that is underdiagnosed and misunderstood. It is typically years before a proper diagnosis is made. During this time, ..... see more
Source : https://link.springer.com/chapter/10.1007/978-3-030-59309-4_10
Different positron emission tomography findings in schizophrenia and narcolepsy type 1 in adolescents and young adults: a preliminary study - PubMed
1 Department of Child Psychiatry and Sleep Center, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan. 2 Department of Medical Imaging and Radiological Sciences, College ..... see more
Narcolepsy type 1 features across the life span: age impact on clinical and polysomnographic phenotype
Narcolepsy type 1 (NT1) is a chronic neurological disorder typically arising during adolescence and young adulthood. Recent studies demonstrated that NT1 presents with age-specific features, especially in children. With this ..... see more
Does Homeostatic Sleep Pressure Buildup Explain Objective Excessive Daytime Sleepiness in Adults With ADHD? An Exploratory Study
Background: Excessive daytime sleepiness (EDS) is central in Attention deficit hyperactivity disorder (ADHD) but its causes remain unclear. see more
Source : https://www.frontiersin.org/articles/10.3389/fpsyt.2021.586528/full
Pre-treatment of blood samples reveal normal blood hypocretin/orexin signal in narcolepsy type 1
Abstract. The hypocretin/orexin system regulates arousal through central nervous system mechanisms and plays an important role in sleep, wakefulness, and energy see more
High nocturnal sleep fragmentation is associated with low T lymphocyte P2Y11 protein levels in narcolepsy type 1
AbstractStudy objectives. Narcolepsy type 1 (NT1) is associated with hypocretin neuron loss. However, there are still unexplained phenotypic NT1 features. We in see more
Source : https://academic.oup.com/sleep/advance-article/doi/10.1093/sleep/zsab062/6168886?login=true
Recognizing and Treating Excessive Daytime Sleepiness in Patients With Narcolepsy | Psychiatrist.com
Article AbstractSleep disorders such as narcolepsy can cause excessive daytime sleepiness (EDS). The diagnosis of narcolepsy is often delayed by years. Clinicians can improve the recognition of EDS and diagnosis ..... see more
Two sides of a coin: differential response to COVID-19 distancing measures in children with narcolepsy.
Narcolepsy is a chronic neurological sleep disorder, debuting before the age of fifteen in one-third of the cases. Narcolepsy has a negative influence on quality of life, with daily functioning ..... see more
Source : https://doi.org/10.5664/jcsm.9040