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Neurobiological mechanisms associated with antipsychotic drug-induced dystonia - PubMed

Neurobiological mechanisms associated with antipsychotic drug-induced dystonia - PubMed

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https://pubmed.ncbi.nlm.nih.gov/32900259/

Dystonia is by far the most intrusive and invalidating extrapyramidal side effect of potent classical antipsychotic drugs. Antipsychotic drug-induced dystonia is classified in both acute and tardive forms. The incidence of drug-induced dystonia is associated with the affinity to inhibitory dopamine ...

  • 8 months 3 weeks
    Acute dystonia was most common with IM use of Haldol for control of acute agitation and less often with Prolixin and Navane.However with 2nd generation antipsychotics incidences of acute dystonia and TD have lessened substantially.With the introduction of Ingrezza and Austedo there has been further relief for TD symptoms.