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Hyperpolarization of the subthalamic nucleus alleviates hyperkinetic movement disorders

Hyperpolarization of the subthalamic nucleus alleviates hyperkinetic movement disorders

Source :

https://www.nature.com/articles/s41598-020-65211-w

Modulation of subthalamic nucleus (STN) firing patterns with injections of depolarizing currents into the STN is an important advance for the treatment of hypokinetic movement disorders, especially Parkinson's disease (PD). Chorea, ballism and dystonia are prototypical examples of hyperkinetic movement disorders.