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The role of glutamate receptors and their interactions with ... : Behavioural Pharmacology

The role of glutamate receptors and their interactions with ... : Behavioural Pharmacology

Source :

https://journals.lww.com/behaviouralpharm/Abstract/9000/The_role_of_glutamate_receptors_and_their.99179.aspx

cal hypothesis of tardive dyskinesia development includes dopaminergic imbalance in the direct and indirect pathways of the basal ganglia, cholinergic deficiency, serotonin receptor disturbances, neurotoxicity, oxidative stress, and changes in synaptic plasticity. Although, the role of the glutamatergic system has been confirmed in preclinical tardive dyskinesia models it seems to have been neglected in recent reviews.