Clinical and neurophysiological characteristics of 89 patients with narcolepsy and cataplexy from the Russian Narcolepsy Network - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36305577/
doi: 10.5664/jcsm.10340. Online ahead of print. 1 Sechenov University, Moscow, Russia. 2 Samara State Medical University, department neurology and neurosurgery, Samara, Russia. 3 Samara State Medical University, Research Institute of...
Conclusions: Clinical and neurophysiological data from this first study of the Russian Narcolepsy Network suggest a similar profile to the recently reported EU-NN data. The more severe and higher percentage of patients with cataplexy and presenting with both excessive daytime sleepiness (EDS) and cataplexy may reflect low awareness of...
Precision Medicine for Idiopathic Hypersomnia - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36150801/
Idiopathic hypersomnia (IH) includes a clinical phenotype resembling narcolepsy (with repeated, short restorative naps), and a phenotype with an excess of sleep, sleep drunkenness, drowsiness, and infrequent long, nonrestorative naps....
Conclusions: Possible mechanisms of IH include deficiencies in arousal systems, inappropriate stimulation of sleep-inducing systems, and long biological night. Treatments now include robust studies of modafinil, clarithromycin, and sodium oxybate.
Inadequate sleep duration may attenuate the anti-inflammatory effects of fish consumption in a healthy Japanese population: A cross-sectional study | British Journal of Nutrition | Cambridge Core
Accepted manuscript Shigemasa Tani* Affiliation: Department of Health Planning Center, Nihon University Hospital, Tokyo, 1018309, Japan Department of Cardiology, Nihon University Hospital, Tokyo, 1018309, Japan Department of Medicine, Division of...
Conclusion/Relevance: Higher fish consumption may be associated with a lower WBC count in the presence of adequate sleep duration and healthy lifestyle behaviors. However, long sleep duration was also related to increased inflammation, even in populations with high fish consumption. Further studies are needed to clarify the causality between...
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Dr Hamid3yrInteresting article that explains -High fish consumption may be associated with lower inflammation, suppressing atherosclerotic cardiovascular disease (ASCVD)
A Comprehensive Review of Daridorexant, a Dual-Orexin Receptor Antagonist as New Approach for the Treatment of Insomnia - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36144776/
Insomnia affects 4.4-4.8% of the world's population, but because the effect of hypnotic drugs is limited and may cause harmful side-effects, scientists are turning their attention to developing drugs that...
Conclusion/Relevance: The use of daridorexant is considered safe, with no clinically significant side-effects including deprivation of next-morning residual effects. In this manuscript we conducted a comprehensive review of daridorexant including pharmacodynamics, animal and human research, pharmacokinetics and safety.
Use of digital screens by adolescents and association on sleep quality: a systematic review
Source : https://www.scielo.br/j/csp/a/Zv7rmV5TVmRGkGWyrxWm4qd/?lang=en
This study aimed to analyze the influence of digital screen use on adolescents' quality of sleep. This systematic review was recorded on PROSPERO (CRD42020203403) and conducted according to PRISMA guidelines....
Conclusion/Relevance: Excessive use of digital screens was associated with worse and shorter sleep, showing, as its main consequences, night awakenings, long sleep latency, and daytime sleepiness. The use of mobile phones before bedtime was associated with poor quality of sleep among adolescents. Our evaluation of the methodological quality of...