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Recent Advances in the Etiology and Neural Pathways Underlying Attention-Deficit and Hyperactivity Disorder - PubMed

Recent Advances in the Etiology and Neural Pathways Underlying Attention-Deficit and Hyperactivity Disorder - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/40678298/

The prevalence of mental disorders is increasing across the European Union, with at least one in four individuals expected to experience a psychiatric condition at some point in their lifetime....

This review links ADHD-related dopamine/norepinephrine dysfunction to circadian disruptions, highlighting their combined impact on symptom severity and sleep regulation. It proposes chronotherapeutic strategies to optimize ADHD treatment and manage comorbid sleep disorders.

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Disinhibition of the Ventral Tegmental Area After Trauma Restores REM Sleep Disturbances and Reduces Long-Term Behavioral Indices of Fear Memory - PubMed

Disinhibition of the Ventral Tegmental Area After Trauma Restores REM Sleep Disturbances and Reduces Long-Term Behavioral Indices of Fear Memory - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/40640076/

Posttraumatic stress disorder (PTSD) is a pathological condition mainly characterized by the inability to extinct fear responses associated with a traumatic event and profound alteration in REM sleep. A decrease...

Disinhibiting VTA dopamine neurons post-trauma preserved REM sleep and improved fear extinction in rats, suggesting REM sleep restoration as a therapeutic target for PTSD-related sleep and memory disturbances.

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The 2025 APA Resource Document explores catatonia’s history, prevalence, diagnostics, differential diagnoses, and treatment—including benzodiazepines and ECT. It also addresses special populations like pediatrics, pregnancy, dementia, and outlines ethical/legal concerns.

Review APA’s latest guidance on catatonia

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Did you know? The American Psychiatric Association recommends structured psychotherapy—like Dialectical Behavior Therapy and Mentalization-Based Treatment—as the gold standard for Borderline Personality Disorder, with medication used only for specific symptoms and always alongside therapy. Person-centered plans and collaboration are key.

Did you know that clinicians are encouraged to use standardized symptom scales at the start of BPD treatment to track progress over time?

 NCCN Guidelines

Did you know that clinicians are encouraged to use standardized symptom scales at the start of BPD treatment to track progress over time?