Clinical Impact of the Implementation Strategies Used to Apply the 2013 Pain, Agitation/Sedation, Delirium or 2018 Pain, Agitation/Sedation, Delirium, Immobility, Sleep Disruption Guideline Recommendations: A Systematic Review and Meta-Analysis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38193764/
Using multiple implementation strategies to adopt PAD/PADIS guideline recommendations may reduce mortality, duration of MV, and ICU LOS. Further prospective, controlled studies are needed to identify the most effective strategies...
Implementation strategies for PAD/PADIS guidelines may reduce mortality, mechanical ventilation duration, and ICU length of stay. Further controlled studies are needed to determine the most effective approaches.
A review of supine position related obstructive sleep apnea: Classification, epidemiology, pathogenesis and treatment
Source : https://pubmed.ncbi.nlm.nih.gov/37722317/
Supine related obstructive sleep apnea (OSA) is the most common clinical and physiological phenotype of OSA. This condition is recognizable by patients, their families and through polysomnographic recordings. Commonly used...
Supine-related OSA is common and associated with increased airway collapsibility. Vibrotactile devices offer promising treatment to reduce supine sleep, supported by growing evidence from randomized controlled trials.
Insufficient sleep and weekend recovery sleep: classification by a metabolomics-based machine learning ensemble
Source : https://pubmed.ncbi.nlm.nih.gov/38036605/
Although weekend recovery sleep is common, the physiological responses to weekend recovery sleep are not fully elucidated. Identifying molecular biomarkers that represent adequate versus insufficient sleep could help advance our...
The study identified changes in glycerophospholipids and sphingolipids as biomarkers of insufficient sleep, suggesting that more than one weekend of recovery sleep is needed for metabolic restoration.
Orexin and Sleep Disturbances in Alpha-Synucleinopathies: a Systematic Review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39031323/
17 studies were included in this systemic review, of which 2 studies on RBD, 10 on PD, 4 on DLB, and 1 on MSA patients. Taken together, RBD and PD...
This review highlights a complex relationship between orexin dysregulation and sleep disturbances in alpha-synucleinopathies, emphasizing the need for further research to clarify orexin's role and potential therapeutic applications.
Sleep quality in eating disorders: A systematic review and meta-analysis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38959584/
Eating disorders (ED) are psychological disorders characterized by dangerous eating behaviours, including protracted fasting and binge eating. Mental disorders comorbidities (e.g., anxiety and depression), as well as sleep difficulties, are...
This study indicates that individuals with eating disorders experience poorer sleep quality, particularly in anorexia nervosa, while specialized treatments may enhance sleep quality, necessitating further investigation into underlying mechanisms.