Altered Brain Functional Connectivity and Peripheral Transcriptomic Profiles in Major Depressive Disorder With Childhood Maltreatment - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40225733/
Background: Childhood maltreatment (CM) is a significant risk factor for major depressive disorder (MDD), yet the underlying biological mechanisms remain unclear. This study aimed to investigate brain functional networks and...
This study links disrupted occipital brain connectivity and immune-related transcriptomic changes to sleep disturbances in major depressive disorder patients with childhood maltreatment, revealing potential biological pathways for sleep dysfunction.
Sleep and male (In)Fertility: A comprehensive overview - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40153995/
Infertility affects millions of couples globally, with male factors contributing up to 50 % of cases. Despite the existing Assisted Reproduction Technologies (ART), decreased sperm quality and male infertility persist....
This review examines how sleep disturbances, particularly insomnia, affect male fertility by exploring hormonal disruptions, reduced sperm quality, and potential biological mechanisms in both human and animal studies.
The Brain Fatigue Syndrome-Symptoms, Probable Definition, and Pathophysiological Mechanisms - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40429267/
Fatigue is a common consequence of traumatic brain injury, neurological diseases or developmental disorders, and systemic inflammatory diseases, including autoimmune conditions that affect the brain. This condition is characterized by...
This review introduces Brain Fatigue Syndrome, a condition marked by cognitive fatigue, emotional instability, and sleep disturbances, linking symptoms to brain injuries and inflammatory mechanisms like astrocyte and mitochondrial dysfunction.
The Pharmacokinetics, Dosage, Preparation Forms, and Efficacy of Orally Administered Melatonin for Non-Organic Sleep Disorders in Autism Spectrum Disorder During Childhood and Adolescence: A Systematic Review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40426828/
Background: To date, it remains unclear which oral doses and preparation forms of melatonin should be recommended for children and adolescents with non-organic sleep disorders and autism spectrum disorder (ASD)....
This systematic review evaluates randomized trials and pharmacokinetic data on oral melatonin use in ASD-related sleep disorders, recommending low-dose, rapid-onset formulations when behavioral interventions prove insufficient.
Wearable Sensors and Artificial Intelligence for Sleep Apnea Detection: A Systematic Review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40387964/
Sleep apnea, a prevalent disorder affecting millions of people worldwide, has attracted increasing attention in recent years due to its significant impact on public health and quality of life. The...
This review examines AI and wearable technologies for sleep apnea detection, highlighting 28 studies. It finds convolutional networks and sensor integration promising for early, accurate diagnosis using real-time data.