Human melanopsin (OPN4) gene polymorphisms: a systematic review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40556870/
The melanopsin (OPN4) gene is crucial in visual and non-visual processes. Certain single-nucleotide polymorphisms (SNPs) of this gene have been linked to altered light sensitivity, photoentrainment, sleep disorders, and metabolic...
This review identifies melanopsin gene variants associated with sleep disorders and chronotype changes, highlighting the P10L, I394T, and R168C SNPs as potential genetic contributors to disrupted circadian regulation.
A bibliometric analysis of wearable device research in sleep science: Trends and hotspots - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40527826/
This study provides a comprehensive overview of the current state of wearable device research in sleep science. By identifying key trends, influential researchers, and emerging research areas, this study offers...
This bibliometric study analyzes trends in wearable sleep device research from 2004–2025, identifying key contributors, emerging hotspots, and technologies crucial to advancing sleep disorder diagnosis and management.
Imaging advances to detect non-motor prodromal markers of Parkinson's disease and explore therapeutic translation opportunities - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40533452/
Parkinson's disease (PD) is a progressive neurological disorder marked by late-emerging motor symptoms, but early non-motor signs like hyposmia and REM sleep behavior disorder may precede diagnosis by years. Identifying...
This review discusses imaging tools to detect early non-motor signs of Parkinson’s disease—like REM sleep behavior disorder—highlighting their value in predicting disease onset and enabling early neuroprotective therapies.
Idiopathic Hypersomnia: Recognition and Management in Psychiatric Practice - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40488724/
Objective: This review of the relationship between idiopathic hypersomnia and psychiatric disorders describes considerations in recognizing and managing complaints of excessive daytime sleepiness (EDS) in patients in psychiatric clinical practice....
This review outlines how idiopathic hypersomnia complicates psychiatric diagnosis and treatment, emphasizing the importance of recognizing hypersomnolence symptoms and addressing comorbidities to improve outcomes in psychiatric clinical practice.
Bringing Attention to a Forgotten Age Group: A Discussion on Late-Onset Bipolar Disorder - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40497172/
Affecting millions worldwide, bipolar disorder is a chronic condition most commonly diagnosed before the age of 50. However, diagnosing bipolar disorder beyond this age bracket presents unique challenges and is...
This case study of a 75-year-old with late-onset bipolar disorder emphasizes diagnostic complexity in elderly patients, particularly regarding symptoms like sleep reduction, and advocates for better age-specific psychiatric guidelines.