Sleep scoring in neurodegenerative diseases: Towards new rules - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40769811/
Standard sleep scoring criteria often fail to accurately describe sleep architecture in patients with neurodegenerative diseases, due to disease-related alterations in neurophysiological variables. Although this issue has long been recognised,...
A novel sleep scoring system tailored for neurodegenerative diseases enhances detection of atypical sleep patterns, offering potential as a non-invasive biomarker. Initial validation shows promise for improved diagnostic accuracy.
Unraveling the relationship between disordered sleep and systemic sclerosis outcomes - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40747600/
Sleep disorders are an under-recognized but significant burden in SSc, driven by complex interactions among disease manifestations and psychological and physiological factors. Early comprehensive assessment and integrated management of sleep...
This review highlights how sleep disturbances in systemic sclerosis—driven by immune, fibrotic, and symptomatic pathways—impact disease outcomes, urging early assessment and integrated management to improve sleep and quality of life.
Joint Trajectories of Insomnia Severity and Quality of Life Among Adults in Opioid Use Disorder Treatment: A Longitudinal Study With Parallel Process Latent Growth Curve Modelling - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40708236/
Sleep health is related to quality of life (QOL) in the general population, yet less is known about the trajectories of sleep and QOL during opioid use disorder (OUD) treatment....
This longitudinal study of 1607 adults in opioid use disorder treatment found that worsening insomnia predicted poorer quality of life, underscoring the need to address sleep early to enhance recovery outcomes.
Recent Advances in the Etiology and Neural Pathways Underlying Attention-Deficit and Hyperactivity Disorder - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40678298/
The prevalence of mental disorders is increasing across the European Union, with at least one in four individuals expected to experience a psychiatric condition at some point in their lifetime....
This review links ADHD-related dopamine/norepinephrine dysfunction to circadian disruptions, highlighting their combined impact on symptom severity and sleep regulation. It proposes chronotherapeutic strategies to optimize ADHD treatment and manage comorbid sleep disorders.
Disinhibition of the Ventral Tegmental Area After Trauma Restores REM Sleep Disturbances and Reduces Long-Term Behavioral Indices of Fear Memory - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40640076/
Posttraumatic stress disorder (PTSD) is a pathological condition mainly characterized by the inability to extinct fear responses associated with a traumatic event and profound alteration in REM sleep. A decrease...
Disinhibiting VTA dopamine neurons post-trauma preserved REM sleep and improved fear extinction in rats, suggesting REM sleep restoration as a therapeutic target for PTSD-related sleep and memory disturbances.