Idiopathic central sleep apnea with periodicity presenting as cheyne-stokes breathing

Source : https://doi.org/10.1016/j.clinph.2021.02.220

Pleasure, addiction, and hypocretin (orexin)

Source : https://www.semel.ucla.edu/sites/default/files/publications/21_pleasure_addiction_hypocretin_mcgregor_thannickal_siegel.pdf

Jazz Pharmaceuticals Presents Phase 3 Study Results of Xywavtm (calcium, magnesium, potassium, and sodium oxybates) Oral Solution in Adult Patients with Idiopathic Hypersomnia at 2021 American Academy of Neurology Annual Meeting

Source : https://www.lelezard.com/en/news-19757248.html

Xywav demonstrated statistically significant differences in change in Epworth Sleepiness Scale score (p-value <0.0001), Patient Global Impression of Change (p-value <0.0001) and the Idiopathic Hypersomnia Severity Scale (p-value <0.0001) The...

Onset of narcolepsy type 1 in a paraneoplastic encephalitis associated with a thymic seminoma

Source : https://jcsm.aasm.org/doi/abs/10.5664/jcsm.9496

Narcolepsy type 1 (NT1) results from probable autoimmune disruption of hypothalamic hypocretinergic neurons. Secondary narcolepsy can occur as a result of other conditions affecting the central nervous system, including limbic...

The Symptom Spectrum of Narcolepsy: Relevance For Diagnosis | NSS

Source : https://doi.org/10.2147/NSS.S278046

It is becoming increasingly clear that the symptom spectrum of narcolepsy is much more extensive, including several symptoms that are not directly related to sleep such as psychiatric symptoms or...