Safety and efficacy of daridorexant in patients with insomnia disorder: results from two multicentre, randomised, double-blind, placebo-controlled, phase 3 trials
Source : https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(21)00436-1/
Daytime functioning is impaired in people with insomnia disorder. Currently available dual orexin receptor antagonists have shown efficacy in insomnia disorder, but do not address all aspects of this disease....
Interpretation: Daridorexant 25 mg and 50 mg improved sleep outcomes, and daridorexant 50 mg also improved daytime functioning, in people with insomnia disorder, with a favourable safety profile.
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Dr Hamid4yrdaridorexant 50 mg also improved daytime functioning, in people with insomnia
Using Telehealth to Deliver Cognitive Behavioral Treatment of Insomnia to a Caregiver of a Person With Alzheimer's Disease
Source : https://connect.springerpub.com/content/sgrjcp/36/1/3
Cognitive behavioral therapy for Insomnia (CBT-I) is the gold standard treatment for insomnia. There is limited access to qualified providers to deliver CBT-I; moreover, there are patient populations who struggle...
Conclusion/Relevance: This case study illustrates the successful implementation of a four-session CBT-I protocol through telehealth with a caregiver of a person with Alzheimer’s disease. Given the success of this case and the conditions for psychological care the recent pandemic has created, continued research into the efficacy of...
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Dr Hamid4yrCognitive behavioral therapy for Insomnia (CBT-I) is great options
Sleep, sleep homeostasis and arousal disturbances in alcoholism - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35122900/
The effects of alcohol on human sleep were first described almost 70 years ago. Since then, accumulating evidences suggest that alcohol intake at bed time immediately induces sleep [reduces the...
Conclusion/Relevance: In this review, a conceptual framework and clinical research focused on understanding the relationship between alcohol and sleep is first described. In the next section, our new and exciting preclinical studies, to understand the cellular and molecular mechanism of how acute and chronic alcohol affects sleep, are described....
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Dr Hamid4yrRepeated use of alcohol leads to the development of tolerance
The association between Diabetes and Excessive Daytime Sleepiness among American adults aged 20-79 years: Findings from the 2015-2018 National Health and Nutrition Examination Surveys - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35121113/
doi: 10.1016/j.annepidem.2022.01.002. Online ahead of print. 1 School of Population and Public Health, University of British Columbia, 2206 East Mall, Vancouver, BC, V6T 1Z3, Canada; Medicine (Neurology), University of British...
Conclusions: Among American adults, diabetes is associated with EDS after controlling for confounding variables. Although the cross-sectional design is a limitation, our findings support further exploration of the role of diabetes in EDS.
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Dr Hamid4yrImport to assess association between EDS and diabetes-care variables.
Telemedicine and insomnia: a comprehensive systematic review and meta-analysis
Source : https://www.sciencedirect.com/science/article/abs/pii/S1389945722000168?via=ihub
Studies showed that telemedicine interventions have a positive effect on improving insomnia in different groups. * CBTI interventions based on telemedicine have a greater effect on improving chronic insomnia than...
Conclusion: The use of telemedicine in treatment of insomnia not only accelerates access to sleep services, but can also improve the efficiency of health services in terms of time and cost, as well as therapeutic effects.
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Dr Hamid4yrtelemedicine interventions have a positive effect on improving insomnia in different groups.