Pfizer/BioNTech SARS-CoV-2 vaccine as a potential trigger for the development of narcolepsy: a case report - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35733336/
Narcolepsy is a rare condition in Israel. Currently, the incidence of narcolepsy following SARS-CoV-2 vaccination in Israel is unknown. We are reporting a case report of a 51-year-old female of...
Relevance: Narcolepsy is a rare condition in Israel. Currently, the incidence of narcolepsy following SARS-CoV-2 vaccination in Israel is unknown. We are reporting a case report of a 51-year-old female of Ashkenazi Jewish descent who was evaluated for complaints of excessive daytime sleepiness and relative functional decline that immediately...
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Dr Hamid4yrThis case is a valuable contribution to the literature as there are no prior reports of type 1 narcolepsy following SARS-CoV-2 vaccination
Once-nightly sodium oxybate (FT218) in the treatment of narcolepsy: a letter to the editor commenting on the recent publication by C. Kushida et al
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189932/
Dear Editor, We read with interest the publication titled "Once-Nightly Sodium Oxybate (FT218) Demonstrated Improvement of Symptoms in a Phase 3 Randomized Clinical Trial in Patients With Narcolepsy," by C....
Relevance: “We hope that our comments are received in the spirit of advancing the practice of sleep medicine with therapeutic use of oxybate in the treatment of narcolepsy.”
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Dr Hamid4yrStudy will help to improve the lives of patients with narcolepsy
Adherence to a Healthy Sleep Pattern and Incidence of Cardiometabolic Multimorbidity Among Hypertensive Patients: A Prospective Study of UK Biobank
Source : https://academic.oup.com/sleep/advance-article/doi/10.1093/sleep/zsac141/6615411?login=false
AbstractStudy Objectives. To investigate whether a healthy sleep pattern would reduce the risk of cardiometabolic multimorbidity (CMM) among hypertensives.Metho
Conclusion: We hope that our comments are received in the spirit of advancing the practice of sleep medicine with therapeutic use of oxybate in the treatment of narcolepsy.
Driving Performance after Bedtime Administration of Daridorexant, Assessed in a Sensitive Simulator - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35426136/
Use of hypnotics is often associated with next-morning residual effects and a higher risk of motor vehicle accidents. Measuring next-morning effects on driving performance is therefore advised by regulatory agencies....
Conclusion/Relevance: Daridorexant showed a lower self-rated driving quality and higher effort compared to placebo on day 2 but not on day 5. In non-insomnia subjects, daridorexant impaired simulated driving after initial but not after repeated dosing. Subjects should be cautioned about driving until they know how daridorexant affects them.
Solriamfetol for the Use of Narcolepsy: A Systematic Review
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188301/
Narcolepsy is one of the most common disorders that cause chronic sleepiness, affecting around one in 2,000 people [ 1, 2]. The disease has a prevalence in Europe and North...
Conclusion/Relevance: We conducted this systematic review using objective measures such as the Epworth Sleepiness Scale and the Maintenance of Wakefulness Test. Overall, cataplexy was not formally evaluated in the four clinical trials; however, it demonstrated that EDS improved in patients with and without cataplexy. More clinical trials are...