Disease Spotlight
Agitation in Alzheimer's Dementia

Test Your Knowledge

Did you know?

Peer to Peer Insights
Profile Image
  • Add Media
  • Saved

6mo
Brexpiprazole's impacts on patients and caregivers in agitation in Alzheimer's dementia - PubMed

Brexpiprazole's impacts on patients and caregivers in agitation in Alzheimer's dementia - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/40717666/

ClinicalTrials.gov Identifier NCT03620981 HIGHLIGHTS: Brexpiprazole improved symptoms of patients with agitation in Alzheimer's dementia. The improvements included not only agitation, but also various behavioral and psychological symptoms of dementia scores....

A phase 2/3 trial in Japanese patients found brexpiprazole 2 mg significantly improved agitation and broader behavioral symptoms in Alzheimer’s dementia, reducing caregiver distress, highlighting dual patient–caregiver benefits.

  • Saved

6mo

Fun Fact! Turns out, your brain might prefer a good night’s sleep over brain teasers. A 2025 Yale-led study found that adults who spent more time in REM and deep sleep had larger volumes in Alzheimer’s-sensitive brain regions, even 17 years later.

Could targeting REM and slow-wave sleep help delay structural brain changes tied to Alzheimer’s?

REM

Could targeting REM and slow-wave sleep help delay structural brain changes tied to Alzheimer’s?

  • Saved

6mo
Background Image DesktopBackground Image Mobile

At AAIC 2025, the Alzheimer’s Association released the first clinical practice guidelines recommending blood‑based biomarkers for Alzheimer’s pathology assessment in mild cognitive impairment or dementia. These less invasive tests aid early diagnosis and allow timely care initiation.

Explore biomarker-guided care now

  • Saved

6mo
Vascular burden, biomarkers and neuropsychiatric symptoms in dementia - PubMed

Vascular burden, biomarkers and neuropsychiatric symptoms in dementia - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/40781963/

Neuropsychiatric symptoms (NPSs) are commonly seen in individuals with dementia and can often worsen outcomes. Therefore, there is a need for an increase in the understanding of the factors at...

Study of dementia patients found agitation significantly associated with ApoE ε4 genotype, while depression, anxiety, and apathy correlated with vascular burden, highlighting genetic and vascular contributions to neuropsychiatric symptoms in Alzheimer’s disease.

  • Saved

6mo
Vascular burden, biomarkers and neuropsychiatric symptoms in dementia - PubMed

Vascular burden, biomarkers and neuropsychiatric symptoms in dementia - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/40781963/

Neuropsychiatric symptoms (NPSs) are commonly seen in individuals with dementia and can often worsen outcomes. Therefore, there is a need for an increase in the understanding of the factors at...